Aktuelle Publikationen

Publikationen aus der Allgemein- und Viszeralchirurgie

Publikationsverzeichnis Prof. Dr. Peter Kienle

1. Originalpublikationen

  • Updated S3-Guideline Ulcerative Colitis. German Society for Digestive and Metabolic Diseases (DGVS).
    Torsten Kucharzik , Axel U. Dignass , Raja Atreya, Bernd Bokemeyer, Philip Esters, Klaus Herrlinger, Klaus Kannengießer, Peter Kienle, Jost Langhorst, Andreas Lügering, Stefan Schreiber, Andreas Stallmach, Jürgen Stein, Andreas Sturm, Niels Teich, Britta Siegmund
    Z Gastroenterol. 2019 Feb;57(2):162-241.
  • Galata C, Kienle P, Weiss C, Seyfried S, Reißfelder C, Hardt J.
    Risk factors for early postoperative complications in patients with Crohn's disease after colorectal surgery other than ileocecal resection or right hemicolectomy.
    Int J Colorectal Dis. 2019 Feb;34(2):293-300.
  • Ronellenfitsch U, Ernst K, Mertens C, Trunk MJ, Ströbel P, Marx A, Kienle P, Post S, Nowak K.
    Extensive intraperitoneal lavage to eliminate intraperitoneal tumor cells in gastrectomy with D2 lymphadenectomy for gastric cancer.
    Tumori. 2018 Oct;104(5):361-368.
  • Galata C, Merx K, Mai S, Gaiser T, Wenz F, Post S, Kienle P, Hofheinz RD, Horisberger K.
    Impact of adjuvant chemotherapy on patients with ypT0-2 ypN0 rectal cancer after neoadjuvant chemoradiation: a cohort study from a tertiary referral hospital.
    World J Surg Oncol. 2018 Aug 2;16(1):156.
  • Hardt J, Kienle P.
    Laparoscopic ventral pouch pexy with acellular dermal matrix (ADM)-a novel technique for the treatment of full-thickness pouch prolapse after restorative proctocolectomy and j-pouch.
    Int J Colorectal Dis. 2018 Nov;33(11):1643-1646.
  • Karampinis I, Keese M, Jakob J, Stasiunaitis V, Gerken A, Attenberger U, Post S, Kienle P, Nowak K.
    Indocyanine Green Tissue Angiography Can Reduce Extended Bowel Resections in Acute Mesenteric Ischemia.
    J Gastrointest Surg. 2018 Dec;22(12):2117-2124.
  • Kienle P, Galata C, Horisberger K, Ried T, Gaiser T.Dynamics of Genome Alterations in Crohn's Disease-Associated Colorectal Carcinogenesis.
    Hirsch D, Wangsa D, Zhu YJ, Hu Y, Edelman DC, Meltzer PS, Heselmeyer-Haddad K, Ott C,
    Clin Cancer Res. 2018 Oct 15;24(20):4997-5011.
  • Seyfried S, Post S, Kienle P, Galata CL.
    The Kono-S anastomosis in surgery for Crohn's disease : First results of a new functional end-to-end anastomotic technique after intestinal resection in patients with Crohn's disease in Germany.
    Chirurg. 2019 Feb;90(2):131-136.
  • Galata C, Weiss C, Hardt J, Seyfried S, Post S, Kienle P, Horisberger K.
    Risk factors for early postoperative complications and length of hospital stay in ileocecal resection and right hemicolectomy for Crohn's disease: a single-center experience.
    Int J Colorectal Dis. 2018 Jul;33(7):937-945.
  • Sandra-Petrescu F, Herrle F, Burkholder I, Kienle P, Hofheinz RD.
    Influence of complete administration of adjuvant chemotherapy cycles on overall and disease-free survival in locally advanced rectal cancer: post hoc analysis of a randomized, multicenter, non-inferiority, phase 3 trial.
    BMC Cancer. 2018 Apr 3;18(1):369
  • Karampinis I, Ronellenfitsch U, Mertens C, Gerken A, Hetjens S, Post S, Kienle P, Nowak K.
    Indocyanine green tissue angiography affects anastomotic leakage after esophagectomy. A retrospective, case-control study.
    Int J Surg. 2017 Dec;48:210-214
  • Merx K, Martens UM, Kripp M, Hoehler T, Geissler M, Gaiser T, Mai S, Kienle P, Belle S, Plöger C, Hieber U, Wenz F, Post S, Hofheinz RD.
    Panitumumab in Combination With Preoperative Radiation Therapy in Patients With Locally Advanced RAS Wild-type Rectal Cancer: Results of the Multicenter Explorative Single-Arm Phase 2 Study NEORIT.
    Int J Radiat Oncol Biol Phys. 2017 Nov 15;99(4):867-875
  • Hardt J, Pilz L, Magdeburg J, Kienle P, Post S, Magdeburg R.
    Preoperative hypoalbuminemia is an independent risk factor for increased high-grade morbidity after elective rectal cancer resection.
    Int J Colorectal Dis. 2017 Oct;32(10):1439-1446.
  • Galata C, Hirsch D, Reindl W, Post S, Kienle P, Boutros M, Gaiser T, Horisberger K.
    Clinical and Histopathologic Features of Colorectal Adenocarcinoma in Crohn's Disease.
    J Clin Gastroenterol. 2018 Aug;52(7):635-640
  • Ronellenfitsch U, Schwarzbach M, Hofheinz R, Kienle P, Nowak K, Kieser M, Slanger TE, Burmeister B, Kelsen D, Niedzwiecki D, Schuhmacher C, Urba S, van de Velde C, Walsh TN, Ychou M, Jensen K.
    Predictors of overall and recurrence-free survival after neoadjuvant chemotherapy for gastroesophageal adenocarcinoma: Pooled analysis of individual patient data (IPD) from randomized controlled trials (RCTs).
    Eur J Surg Oncol. 2017 Aug;43(8):1550-1558.
  • Schoenberg MB, Magdeburg R, Kienle P, Post S, Eisser PP, Kähler G.
    Hybrid transgastric appendectomy is feasible but does not offer advantages compared with laparoscopic appendectomy: Results from the transgastric appendectomy study.
    Surgery. 2017 Aug;162(2):295-302
  • Grott M, Horisberger K, Weiß C, Kienle P, Hardt J.
    Resection enterostomy versus Hartmann's procedure for emergency colonic resections.
    Int J Colorectal Dis. 2017 Aug;32(8):1171-1177.
  • Honeck P, Kienle P, Huck N, Neisius A, Thüroff J, Stein R.
    Adenocarcinoma in Continent Anal Urinary Diversion: Is a Sigma Rectum Pouch a Surgical Option After Failed Ureterosigmoidostomy?
    Urology. 2017 May;103:209-213.
  • Attenberger UI, Ong MM, Rathmann N, Doyon F, Kienle P, Hofheinz RD, Pilz LR, Dinter DJ, Schoenberg SO, Hausmann D
    mMRI at 3.0 T as an Evaluation Tool of Therapeutic Response to Neoadjuvant CRT in Patients with Advanced-stage Rectal Cancer.
    Anticancer Res. 2017 Jan;37(1):215-222.
  • Magdeburg J, Glatz N, Post S, Kienle P, Rickert A
    Long-term functional outcome of colonic resections: how much does fecal impairment influence quality of life?
    Colorectal Dis 2016 Nov; 18(11):O405-O413
  • Vassilev G, Hasenberg T, Krammer J, Kienle P, Ronellenfitsch U, Otto M
    The phase angle of the bioelectrical analysis as predictor of post-bariatric weight loss outcome.
    Obes Surg 2016 Jul 27 Epub ahead of print
  • Weidner P, Söhn M, Gutting T, Friedrich T, Gaiser T, Magdeburg RJ, Kienle P, Ruh H, Hopf C, Behrens HM, Röcken C, Hanoch T, Seger R, Ebert MP, Burgermeister E
    Myotubularin-related protein 7 inhibits insulin signaling in colorectal cancer.
    Oncotarget 2016 Jul 7 Epub ahead of print
  • Belharazem D, Magdeburg J, Berton AK, Beissbarth I, Sauer C, Sticht C, Marx A, Hofheinz R, Post S, Kienle P, Ströbel P
    Carcinoma of the colon and rectum with deregulation of insulin-like growth factor 2 signaling: clinical and molecular implications.
    J Gastroenterol 2016 Oct;51(10):971-84
  • Hardt J, Mai S, Weiß C, Kienle P, Magdeburg J
    Abdominoperineal resection and perineal wound healing in recurrent, persistent, or primary anal carcinoma.
    Int J Colorectal Dis 2016 Jun;31(6):1197-203
  • Horisberger K, Rickert A, Templin S, Post S, Kienle P
    Laparoscopic ventral mesh rectopexy in complex pelvic floor disorder.
    Int J Colorectal Dis 2016 May; 31(5):991-6
  • Herrle F, Sandra-Petrescu F, Weiss C, Post S, Runkel N, Kienle P
    Quality of life and timing of stoma closure in patients with rectal cancer undergoing low anterior resection with diverting stoma: a multicenter longitudinal observational study.
    Dis Colon Rectum 2016 Apr;59(4):281-90
  • Otto M, Elrefai M, Krammer J, Weiß C, Kienle P, Hasenberg T
    Sleeve gastrectomy and Roux-en-Y gastric bypass lead to comparable changes in body composition after adjustment for initial body mass index.
    Obes Surg 2016 Mar;26(3):479-85
  • Hardt J, Seyfried S, Weiß C, Post S, Kienle P, Herrle F
    A pilot single-centre randomized trial assessing safety and efficacy of lateral pararectus abdominis compared with transrectus abdominis muscle stoma placement in patients with temporary loop ileostomies: the PATRASTOM trial.
    Colorectal Dis. 2016 Feb;18(2):O81-90
  • Herrle F, Diener MK, Freudenberg S, Willeke F, Kienle P, Boenninghoff R, Weiss C, Partecke LI, Schuld J, Post S
    Single-Layer Continuous Versus Double-Layer Continuous Suture in Colonic Anastomoses-a Randomized Multicentre Trial (ANATECH Trial).
    J Gastrointest Surg. 2016 Feb;20(2):421-30
  • Sandra-Petrescu F, Herrle F, Hinke A, Rossion I, Suelberg H, Post S, Hofheinz RD, Kienle P
    CoCStom trial: study protocol for a randomised trial comparing completeness of adjuvant chemotherapy after early versus late diverting stoma closure in low anterior resection for rectal cancer.
    BMC Cancer. 2015 Nov 21;15:923
  • Téoule P, Birgin E, Zaltenbach B, Kähler G, Wilhelm TJ, Kienle P, Rückert F
    A Retrospective, Unicentric Evaluation of Complicated Diverticulosis Jejuni: Symptoms, Treatment, and Postoperative Course.
    Front Surg. 2015 Nov 13;2:57
  • Doyon F, Attenberger UI, Dinter DJ, Schoenberg SO, Post S, Kienle P
    Clinical relevance of morphologic MRI criteria for the assessment of lymph nodes in patients with rectal cancer.
    Int J Colorectal Dis. 2015 Nov;30(11):1541-6.
  • Attenberger UI, Morelli JN, Budjan J, Herold A, Kienle P, Kleine W, Häcker A, Baumann C, Heinzelbecker J, Schoenberg SO, Michaely HJ
    The value of dynamic magnetic resonance imaging in interdisciplinary treatment of pelvic floor dysfunction.
    Abdom Imaging. 2015 Oct;40(7):2242-7
  • Kripp M, Horisberger K, Mai S, Kienle P, Gaiser T, Post S, Wenz F, Merx K, Hofheinz RD
    Does s the Addition of Cetuximab to Radiochemotherapy Improve Outcome of Patients with Locally Advanced Rectal Cancer? Long-Term Results from Phase II Trials.
    Gastroenterol Res Pract. 2015;2015:273489.
  • Rickert A, Krüger CM, Runkel N, Kuthe A, Köninger J, Jansen-Winkeln B, Gutt CN, Marcus DR, Hoey B, Wente MN, Kienle P
    The TICAP-Study (titanium clips for appendicular stump closure): A prospective multicentre observational study on appendicular stump closure with an innovative titanium clip.
    BMC Surg. 2015 Jul 17;15:85
  • Otto M, Färber J, Haneder S, Michaely H, Kienle P, Hasenberg T
    Postoperative changes in body composition--comparison of bioelectrical impedance analysis and magnetic resonance imaging in bariatric patients.
    Obes Surg. 2015 Feb;25(2):302-9
  • Preiß JC, Bokemeyer B, Buhr HJ, Dignaß A, Häuser W, Hartmann F, Herrlinger KR, Kaltz B, Kienle P, Kruis W, Kucharzik T, Langhorst J, Schreiber S, Siegmund B, Stallmach A, Stange EF, Stein J, Hoffmann JC; German Society of Gastroenterology
    Updated German clinical practice guideline on "Diagnosis and treatment of Crohn's disease" 2014].
    Z Gastroenterol. 2014 Dec;52(12):1431-84
  • Otto M, Kautt S, Kremer M, Kienle P, Post S, Hasenberg T
    Handgrip strength as a predictor for post bariatric body composition.
    Obes Surg. 2014 Dec;24(12):2082-8.
  • Jakob J, Marenda D, Sold M, Schlüter M, Post S, Kienle P
    Quality of documentation of intraoperative and postoperative complications : improvement of documentation for a nationwide quality assurance program and comparison with routine data.
    Chirurg. 2014 Aug;85(8):705-10.
  • Attenberger UI, Pilz LR, Morelli JN, Hausmann D, Doyon F, Hofheinz R, Kienle P, Post S, Michaely HJ, Schoenberg SO, Dinter DJ
    Multi-parametric MRI of rectal cancer - do quantitative functional MR measurements correlate with radiologic and pathologic tumor stages?
    Eur J Radiol. 2014 Jul;83(7):1036-43
  • Rickert A, Aliyev R, Belle S, Post S, Kienle P, Kähler G
    Oncologic colorectal resection after endoscopic treatment of malignant polyps: does endoscopy have an adverse effect on oncologic and surgical outcomes?
    Gastrointest Endosc. 2014 Jun;79(6):951-60
  • Schwaab J, Horny HP, Jonescheit J, Metzgeroth G, Schafhausen P, Gaiser T, Marx A, Kienle P, Hofmann WK, Reiter A
    Mast cell sarcoma mimicking metastatic colon carcinoma.
    Ann Hematol. 2014 Jun;93(6):1067-9.
  • Dusch N, Weiss C, Ströbel P, Kienle P, Post S, Niedergethmann M
    Factors Predicting Long-Term Survival Following Pancreatic Resection for Ductal Adenocarcinoma of the Pancreas: 40 Years of Experience.
    J Gastrointest Surg. 2014 Apr;18(4):674-81.
    Horisberger K, Rothenhoefer S, Kripp M, Hofheinz RD, Post S, Kienle P
    Impaired continence function five years after intensified chemoradiation in patients with locally advanced rectal cancer.
    Eur J Surg Oncol. 2014 Feb;40(2):227-33.
  • Hardt J, Meerpohl JJ, Metzendorf MI, Kienle P, Post S, Herrle F
    Lateral pararectal versus transrectal stoma placement for prevention of parastomal herniation.
    Cochrane Database Syst Rev. 2013 Nov 22;(11)
  • Rickert A, Herrle F, Doyon F, Post S, Kienle P
    Influence of conversion on the perioperative and oncologic outcomes of laparoscopic resection for rectal cancer compared with primarily open resection.
    Surg Endosc. 2013 Dec;27(12):4675-83.
  • Ronellenfitsch U, Schwarzbach M, Hofheinz R, Kienle P, Kieser M, Slanger TE, Burmeister B, Kelsen D, Niedzwiecki D, Schuhmacher C, Urba S, van de Velde C, Walsh T, Ychou M, Jensen K
    Preoperative chemo(radio)therapy versus primary surgery for gastroesophageal adenocarcinoma: systematic review with meta-analysis combining individual patient and aggregate data.
    Eur J Cancer. 2013 Oct;49(15):3149-58.
  • Ronellenfitsch U, Schwarzbach M, Hofheinz R, Kienle P, Kieser M, Slanger TE, Jensen K; GE
    Perioperative chemo(radio)therapy versus primary surgery for resectable adenocarcinoma of the stomach, gastroesophageal junction, and lower esophagus.
    Cochrane Database Syst Rev. 2013 May 31; (5)
  • Schiessling S, Leowardi C, Kienle P, Antolovic D, Knebel P, Bruckner T, Kadmon M, Seiler CM, Büchler MW, Diener MK, Ulrich A
    Laparoscopic versus conventional ileoanal pouch procedure in patients undergoing elective restorative proctocolectomy (LapConPouch Trial)-a randomized controlled trial.
    Langenbecks Arch Surg. 2013 Aug;398(6):807-16
  • Dusch N, Goranova D, Herrle F, Niedergethmann M, Kienle P
    Randomized controlled trial: comparison of two surgical techniques for closing the wound following ileostomy closure: purse string vs direct suture.
    Colorectal Dis. 2013 Aug;15(8):1033-40.
  • Kaehler G, Schoenberg MB, Kienle P, Post S, Magdeburg R
    Transgastric appendicectomy.
    Br J Surg. 2013 Jun;100(7):911-5.
  • Konanz J, Herrle F, Weiss C, Post S, Kienle P
    Quality of life of patients after low anterior, intersphincteric, and abdominoperineal resection for rectal cancer--a matched-pair analysis.
    Int J Colorectal Dis. 2013 May;28(5):679-88.
  • Hardt J, Schwarzbach M, Hasenberg T, Post S, Kienle P, Ronellenfitsch U
    The effect of a clinical pathway for enhanced recovery of rectal resections on perioperative quality of care.
    Int J Colorectal Dis. 2013 Jul;28(7):1019-26.
  • Rickert A, Kienle P, Kuthe A, Baumann P, Engemann R, Kuhlgatz J, von Frankenberg M, Knaebel HP, Büchler MW
    A randomised, multi-centre, prospective, observer and patient blind study to evaluate a non-absorbable polypropylene mesh vs. a partly absorbable mesh in incisional hernia repair.
    Langenbecks Arch Surg. 2012 Dec;397(8):1225-34.
  • Rothenhoefer S, Herrle F, Herold A, Joos A, Bussen D, Kieser M, Schiller P, Klose C, Seiler CM, Kienle P, Post S
    DeloRes trial: study protocol for a randomized trial comparing two standardized surgical approaches in rectal prolapse - Delorme's procedure versus resection rectopexy.
    Trials. 2012 Aug 29;13:155.
  • Hofheinz RD, Wenz F, Post S, Matzdorff A, Laechelt S, Hartmann JT, Müller L, Link H, Moehler M, Kettner E, Fritz E, Hieber U, Lindemann HW, Grunewald M, Kremers S, Constantin C, Hipp M, Hartung G, Gencer D, Kienle P, Burkholder I, Hochhaus A
    Chemoradiotherapy with capecitabine versus fluorouracil for locally advanced rectal cancer: a randomised, multicentre, non-inferiority, phase 3 trial.
    Lancet Oncol. 2012 Jun;13(6):579-88.
  • Kripp M, Wieneke J, Kienle P, Welzel G, Brade J, Horisberger K, Wenz F, Post S, Gencer D, Hofmann WK, Hofheinz RD
    Intensified neoadjuvant chemoradiotherapy in locally advanced rectal cancer -- impact on long-term quality of life.
    Eur J Surg Oncol. 2012 Jun;38(6):472-7
  • Ronellenfitsch U, Schwarzbach M, Kring A, Kienle P, Post S, Hasenberg T
    The effect of clinical pathways for bariatric surgery on perioperative quality of care.
    Obes Surg. 2012 May;22(5):732-9.
  • Rickert A, Bönninghoff R, Post S, Walz M, Runkel N, Kienle P
    Appendix stump closure with titanium clips in laparoscopic appendectomy.
    Langenbecks Arch Surg. 2012 Feb;397(2):327-31
  • Schwarzbach M, Hasenberg T, Linke M, Kienle P, Post S, Ronellenfitsch U
    Perioperative quality of care is modulated by process management with clinical pathways for fast-track surgery of the colon.
    Int J Colorectal Dis. 2011 Dec;26(12):1567-75.
  • Erben P, Ströbel P, Horisberger K, Popa J, Bohn B, Hanfstein B, Kähler G, Kienle P, Post S, Wenz F, Hochhaus A, Hofheinz RD
    KRAS and BRAF mutations and PTEN expression do not predict efficacy of cetuximab-based chemoradiotherapy in locally advanced rectal cancer.
    Int J Radiat Oncol Biol Phys. 2011 Nov 15;81(4):1032-8
    Braun A, Schönfeld U, Welsch T, Kadmon M, Funke B, Gotthardt D, Zahn A, Autschbach F, Kienle P, Zharnikov M, Grunze M, Stremmel W, Ehehalt R
    Reduced hydrophobicity of the colonic mucosal surface in ulcerative colitis as a hint at a physicochemical barrier defect.
    Int J Colorectal Dis. 2011 Aug;26(8):989-98. doi: 10.1007/s00384-011-1190-z.
  • Schwaab J, Horisberger K, Ströbel P, Bohn B, Gencer D, Kähler G, Kienle P, Post S, Wenz F, Hofmann WK, Hofheinz RD, Erben P
    Expression of Transketolase like gene 1 (TKTL1) predicts disease-free survival in patients with locally advanced rectal cancer receiving neoadjuvant chemoradiotherapy.
    BMC Cancer. 2011 Aug 19;11:363.
  • Herrle F, Hasenberg T, Fini B, Jonescheit J, Shang E, Kienle P, Post S, Niedergethmann M
    Open abdomen 2009. A national survey of open abdomen treatment in Germany].
    Chirurg. 2011 Aug;82(8):684-90.
  • Rickert A, Willeke F, Kienle P, Post S
    Management and outcome of anastomotic leakage after colonic surgery.
    Colorectal Dis. 2010 Oct;12(10 Online):e216-23.
  • Niedergethmann M, Dusch N, Widyaningsih R, Weiss C, Kienle P, Post S
    Risk-adapted anastomosis for partial pancreaticoduodenectomy reduces the risk of pancreatic fistula: a pilot study.
    World J Surg. 2010 Jul;34(7):1579-86.
  • Seiler C, Baumann P, Kienle P, Kuthe A, Kuhlgatz J, Engemann R, V Frankenberg M, Knaebel H
    A randomised, multi-centre, prospective, double blind pilot-study to evaluate safety and efficacy of the non-absorbable Optilene Mesh Elastic versus the partly absorbable Ultrapro Mesh for incisional hernia repair.
    BMC Surg. 2010 Jul 12;10:21.
  • Jakob J, Hinzpeter M, Weiss C, Weiss J, Schlüter M, Post S, Kienle P
    Evaluation of data on surgical complications after cholecystectomy submitted to a nationwide quality assurance program (BQS) in Germany].
    Chirurg. 2010 Jun;81(6):563-7
  • Braun A, Treede I, Gotthardt D, Tietje A, Zahn A, Ruhwald R, Schoenfeld U, Welsch T, Kienle P, Erben G, Lehmann WD, Fuellekrug J, Stremmel W, Ehehalt R
    Alterations of phospholipid concentration and species composition of the intestinal mucus barrier in ulcerative colitis: a clue to pathogenesis.
    Inflamm Bowel Dis. 2009 Nov;15(11):1705-20.
  • Leowardi C, Hinz U, Tariverdian M, Kienle P, Herfarth C, Ulrich A, Kadmon M
    Long-term outcome 10 years or more after restorative proctocolectomy and ileal pouch-anal anastomosis in patients with ulcerative colitis.
    Langenbecks Arch Surg. 2010 Jan;395(1):49-56
  • Löffler T, Welsch T, Mühl S, Hinz U, Schmidt J, Kienle P
    Long-term success rate after surgical treatment of anorectal and rectovaginal fistulas in Crohn’s disease.
    Int J Colorectal Dis 2009; 24 (5):521-6
  • Horisberger K, Treschl A, Mai S, Barreto-Miranda M, Kienle P, Ströbel P, Erben P, Woernle C, Dinter D, Kähler G, Hochhaus A, Post S, Willeke F, Wenz F, Hofheinz RD; MARGIT
    Cetuximab in combination with capecitabine, irinotecan, and radiotherapy for patients with locally advanced rectal cancer: results of a Phase II MARGIT trial.
    Int J Radiat Oncol Biol Phys. 2009 Aug 1;74(5):1487-93
  • Erben P, Horisberger K, Muessle B, Müller MC, Treschl A, Ernst T, Kähler G, Ströbel P, Wenz F, Kienle P, Post S, Hochhaus A, Willeke F, Hofheinz RD
    mRNA expression of platelet-derived growth factor receptor-beta and C-KIT: correlation with pathologic response to cetuximab-based chemoradiotherapy in patients with rectal cancer.
    Int J Radiat Oncol Biol Phys. 2008 Dec 1;72(5):1544-50
  • Keller M, Jost R, Haunstetter CM, Sattel H, Schroeter C, Bertsch U, Cremer F, Kienle P, Tariverdian M, Kloor M, Gebert J, Brechtel A
    Psychosocial outcome following genetic risk counselling for familial colorectal cancer. A comparison of affected patients and family members.
    Clin Genet. 2008 Nov;74(5):414-24.
  • Findeisen P, Röckel M, Nees M, Röder C, Kienle P, Von Knebel Doeberitz M, Kalthoff H, Neumaier M
    Systematic identification and validation of candidate genes for detection of circulating tumor cells in peripheral blood specimens of colorectal cancer patients.
    Int J Oncol. 2008 Nov;33(5):1001-10
  • Schwitalle Y, Kloor M, Eiermann S, Linnebacher M, Kienle P, Knaebel HP, Tariverdian M, Benner A, von Knebel Doeberitz M
    Immune response against frameshift-induced neopeptides in HNPCC patients and healthy HNPCC mutation carriers.
    Gastroenterology. 2008 Apr;134(4):988-97
  • Rahbari NN, Diener MK, Fischer L, Wente MN, Kienle P, Büchler MW, Seiler CM
    A concept for trial institutions focussing on randomised controlled trials in surgery.
    Trials. 2008 Jan 24;9:3. doi: 10.1186/1745-6215-9-3.
  • Welsch T, Müller SA, Ulrich A, Kischlat A, Hinz U, Kienle P, Büchler MW, Schmidt J, Schmied B
    C-reactive protein as early predictor for infectious postoperative complications in rectal surgery.
    Int J Colorectal Dis. 2007 Dec;22(12):1499-507.
  • Köninger J, Müller-Stich BP, Autschbach F, Kienle P, Weitz J, Büchler MW, Gutt CN
    Endoscopic posterior mesorectal resection as an option to combine local treatment of early stage rectal cancer with partial mesorectal lymphadenectomy.
    Langenbecks Arch Surg. 2007 Sep;392(5):567-71
  • Tariverdian M, Leowardi C, Hinz U, Welsch T, Schmidt J, Kienle P
    Quality of life after restorative proctocolectomy for ulcerative colitis: preoperative status and long-term results.
    Inflamm Bowel Dis. 2007 Oct;13(10):1228-35.
  • Ulrich A, Himmer K, Koch M, Kienle P, Büchler MW, Weitz J
    Location of rectal cancer within the circumference of the rectum does not influence lymph node status.
    Ann Surg Oncol. 2007 Aug;14(8):2257-62.
  • Antolovic D, Koch M, Galindo L, Wolff S, Music E, Kienle P, Schemmer P, Friess H, Schmidt J, Büchler MW, Weitz J
    Hepaticojejunostomy--analysis of risk factors for postoperative bile leaks and surgical complications.
    J Gastrointest Surg. 2007 May;11(5):555-61
  • Ulrich A, Schwerdt J, Z'graggen K, Kienle P, Weitz J, Büchler MW
    Acceptance of neoadjuvant short-term radiotherapy: a survey under surgeons and radiotherapists.
    Langenbecks Arch Surg. 2007 Sep;392(5):525-33.
  • Welsch T, Hinz U, Löffler T, Muth G, Herfarth C, Schmidt J, Kienle P
    Early re-laparotomy for post-operative complications is a significant risk factor for recurrence after ileocaecal resection for Crohn's disease.
    Int J Colorectal Dis. 2007 Sep;22(9):1043-9.
  • Weitz J, Kienle P, Schmidt J, Friess H, Büchler MW
    Portal vein resection for advanced pancreatic head cancer.
    J Am Coll Surg. 2007 Apr;204(4):712-6.
  • Seiler CM, Kellmeyer P, Kienle P, Büchler MW, Knaebel HP; INSECT Study Group
    Assessment of the ethical review process for non-pharmacological multicentre studies in Germany on the basis of a randomised surgical trial.
    J Med Ethics. 2007 Feb;33(2):113-8.
  • Antolovic D, Kienle P, Knaebel HP, Schmidt J, Gutt CN, Weitz J, Koch M, Büchler MW, Seiler C
    Totally laparoscopic versus conventional ileoanal pouch procedure--design of a single-centre, expertise based randomised controlled trial to compare the laparoscopic and conventional surgical approach in patients undergoing primary elective restorative proctocolectomy--LapConPouch-Trial.
    BMC Surg. 2006 Nov 24;6:13.
  • Koch M, Kienle P, Logan E, Antolovic D, Galindo L, Schmitz-Winnenthal FH, Schmidt J, Herfarth C, Weitz J
    Detection of disseminated tumor cells in liver biopsies of colorectal cancer patients is not associated with a worse prognosis.
    Ann Surg Oncol. 2007 Feb;14(2):810-7
    Mehrabi A, Yetimoglu CL, Nickkholgh A, Kashfi A, Kienle P, Konstantinides L, Ahmadi MR, Fonouni H, Schemmer P, Friess H, Buchler MW, Schmidt J, Gutt
    Development and evaluation of a training module for the clinical introduction of the da Vinci robotic system in visceral and vascular surgery.
    Surg Endosc Sep;20(9):1376-82
  • Knebel P, Froehlich B, Knaebel HP, Kienle P, Luntz SP, Buechler MW, Seiler CM
    Comparison of Venae Sectio vs. modified Seldinger Technique for Totally Implantable Access Ports; Portas-Trial [ISRCTN 52368201].
    Trials 2006 Jun 8;7:20
  • 14. Koch M, Antolovic D, Kienle P, Horstmann J, Herfarth C, von Knebel Doeberitz M, Weitz J
    Increased detection rate and potential prognostic impact of disseminated tumor cells in patients undergoing endorectal ultrasound for rectal cancer.
    Int J Colorectal Dis. 2007 Apr;22(4):359-65
  • Seiler CM, Frohlich BE, Dorsam UJ, Kienle P, Buchler MW, Knaebel HP
    Surgical technique for totally implantable access ports (TIAP) needs improvement: a multivariate analysis of 400 patients.
    J Surg Oncol 2006; 93: 24-29
  • Engel C, Forberg J, Holinski-Feder E, Pagenstecher C, Plaschke J, Kloor M, Poremba C, Pox CP, Ruschoff J, Keller G, Dietmaier W, Rummele P, Friedrichs N, Mangold E, Buettner R, Schackert HK, Kienle P, Stemmler S, Moeslein G, Loeffler M; German HNPCC Consortium
    Novel strategy for optimal sequential application of clinical criteria, immunohistochemistry and microsatellite analysis in the diagnosis of hereditary nonpolyposis colorectal cancer.
    Int J Cancer 2006; 118:115-122
  • Buckowitz A, Knaebel HP, Benner A, Blaker H, Gebert J, Kienle P, von Knebel Doeberitz M, Kloor M
    Microsatellite instability in colorectal cancer is associated with local lymphocyte infiltration and low frequency of distant metastases.
    Br J Cancer 2005; 92: 1746-1753
  • Woerner SM, Kloor M, Mueller A, Rueschoff J, Friedrichs N, Buettner R, Buzello M, Kienle P, Knaebel HP, Kunstmann E, Pagenstecher C, Schackert HK, Moslein G, Vogelsang H, von Knebel Doeberitz M, Gebert JF; German HNPCC Consortium
    Microsatellite instability of selective target genes in HNPCC-associated colon adenomas.
    Oncogene 2005; 24: 2525-2535
  • Antolovic D, Koch M, Bohlmann I, Kienle P, Buchler M, Weitz J
    Short description of an alternative simplified method for screening recombinant clones within the "AdEasy-System" by Duplex-PCR.
    BMC Biotechnol 2005; 11;5:1
  • Kuntz C, Kienle P, Schmeding M, Benner A, Autschbach F, Schwalbach P
    Comparison of laparoscopic versus conventional technique in colonic and liver resection in a tumor-bearing small animal model
    Surg Endosc 2002; 16: 1175-81, Impactpunkte 2,374 (2001)
  • Lehnert T, Rudek B, Kienle P, Buhl K, Herfarth C
    Impact of diagnostic laparoscopy on the management of gastric cancer: prospective study of 120 consecutive patients with primary gastric adenocarcinoma.
    Br J Surg 2002; 89(4):471-5
  • Koch M, Weitz J, Kienle P, Schrodel A, Benner A, Willeke F, Lehnert T, Herfarth C, von Knebel Doeberitz M
    Comparative analysis of tumor cell dissemination in mesenteric, central, and peripheral venous blood in patients with colorectal cancer
    Arch Surg 2001, 136: 85-89
  • Wüllenweber HP, Sutter C, Kadmon M, Willeke F, Kienle P, Benner A, Autschbach F, Herfarth Ch, von Knebel Doeberitz M, Gebert J
    Evaluation of Bethesda Guidelines in Relation to Microsatellite Instability
    Dis Colon Rectum 2001, 44(9):1281-9
  • Gudemann CJ, Weitz J, Kienle P, Lacroix J, Wiesel MJ, Soder M, Benner A, Staehler G, Doeberitz MV
    Detection of hematogenous micrometastasis in patients with transitional cell carcinoma
    J Urol 2000; 164(2):532-536
  • Weitz J, Koch M, Kienle P, Schrodel A, Willeke F, Benner A, Lehnert T, Herfarth C, von Knebel Doeberitz M
    Detection of hematogenic tumor cell dissemination in patients undergoing resection of liver metastases of colorectal cancer
    Ann Surg 2000; 232(1):66-72
  • Weitz J, Koch M, Kienle P, Willeke F, Lehnert T, Herfarth C, von Knebel Doeberitz M
    Intraoperative Tumorzellaussaat während der Resektion von Lebermetastasen kolorektaler Karzinome
    Langenbecks Arch Chir, Forumsband 2000: 149-152
  • Koch M, Weitz J, Kienle P, Willeke F, Lehnert T, Herfarth C, von Knebel Doeberitz M
    Nachweis von Kolonkarzinomzellen im Mesenterialvenenblut im Vergleich zum peripheren Blut
    Langenbecks Arch Chir 1999; Suppl I: 179-180
  • Huber FX, Stern J, Hinz U, Werle E, Haack D, Kienle P, Heuschen U, Aulmann M, Decker-Baumann C, Herfarth C
    Effects of restorative proctocolectomy on renal and adrenal function
    Dis Colon Rectum 1999; 42(10):1318-24
  • Reinshagen S, Heß T, Kienle P, Kuntz C, Stern J, Herfarth C
    Perianales und perirektales Fistelleiden – welche Diagnostik ist sinnvoll?
    Langenbecks Arch Chir 1999; Suppl I: 1144-1145
  • Weitz J, Kienle P, Magener A, Koch M, Schrodel A, Willeke F, Autschbach F, Lacroix J, Lehnert T, Herfarth C, von Knebel Doeberitz M
    Detection of disseminated colorectal cancer cells in lymph nodes, blood and bone marrow
    Clin Cancer Res 1999; 5(7):1830-6
  • Weitz J, Kienle P, Lacroix J, Willeke F, Benner A, Lehnert T, Herfarth C, von Knebel Doeberitz M
    Dissemination of tumor cells in patients undergoing surgery for colorectal cancer
    Clin Cancer Res 1998; 4(2):343-8
  • Surh S, Kienle P, Stern J, Herfarth C
    Passive electrostimulation therapy of the anal sphincter is inferior to active biofeedback training
    Langenbecks Arch Chir 1998; Suppl I: 976-8
  • Weitz J, Kienle P,  Magener A, Willeke F, Lehnert T, Herfarth C, von Knebel Doeberitz M
    Nachweis isolierter disseminierter Tumorzellen kolorektaler Karzinome in Lymphknoten
    Langenbecks Arch Chir 1998; Suppl I: 319-322
  • Kuntz C, Kienle P, Buhl K, Glaser F, Herfarth C
    Flexible endoscopic ultrasonography of colonic tumors: indications and results
    Endoscopy 1997 Nov; 29(9):865-70
  • Weitz J, Kienle P,  Lacroix J, Willeke F, Lehnert T, Herfarth C, von Knebel Doeberitz M
    Detektion hämatogener Tumorzelldissemination kolorektaler Karzinome
    Langenbecks Arch Chir 1997; Suppl I: 733-736
  • Weitz J, Kienle P, Schmidt H, Klar E, Martin E, Herfarth C
    pHi value as a prognostic parameter in septic and polytrauma patients
    Langenbecks Arch Chir Suppl 1996; 113: 334-7
  • Blind E, Raue F, Kienle P, Schroth J, Grauer A, Kabay A, Brugger P, Ziegler R
    Development and validation of an assay to measure bioactivity of human
    calcitonin in vitro using T47D cell membranes
    Anal Biochem 1993; 212(1):91-7

2. Übersichtsarbeiten

  • Hardt J, Meerpohl JJ, Metzendorf MI, Kienle P, Post S, Herrle F.
  • Lateral pararectal versus transrectal stoma placement for prevention of parastomal herniation.
    Cochrane Database Syst Rev. 2019 Apr 24;4:CD009487.
  • Transanal total mesorectal excision-a critical appraisal.
    Holmer C, Benz S, Fichtner-Feigl S, Jehle EC, Kienle P, Post S, Schiedeck T, Weitz J, Kreis ME.
    Chirurg. 2019 Jun;90(6):478-486.
  • Impact of Modern Drug Therapy on Surgery: Crohn's Disease.
    Kienle P.
    Visc Med. 2018 Dec;34(6):422-425. doi: 10.1159/000495127. Epub 2018 Nov 30.
  • Hardt J, Kienle P.
    The technique of restorative proctocolectomy with ileal J‑pouch : Standards and controversies.
    Chirurg. 2017 Jul;88(7):559-565.
  • Horisberger K, Kienle P.
    Surgery in Crohn's disease
    Chirurg. 2015 Nov;86(11):1083-94.
  • Rickert A, Kienle P.
    Laparoscopic surgery for rectal prolapse and pelvic floor disorders.
    World J Gastrointest Endosc. 2015 Sep 10;7(12):1045-54
  • Hardt J, Kienle P.
    Occult and Manifest Colorectal Carcinoma in Ulcerative Colitis: How Does It Influence Surgical Decision Making?
    Viszeralmedizin. 2015 Aug;31(4):252-7
  • Horisberger K., Kienle P.
    Rektumkarzinom - Teil 2: Operationstechnik
    Allgemein- und Viszeralchirurgie up2date 06 2013; 7: 163 – 181
  • Esters P, Kienle P, Dignass A.
    Treatment of stenoses caused by Crohn's disease
    Dtsch Med Wochenschr. 2013 Sep;138(36):1785-9
  • Kienle P, Horisberger K.
    Transabdominal procedures for functional bowel diseases.
    Chirurg. 2013 Jan;84(1):21-9
  • Welsch T, Büchler MW, Kienle P.
    Recalling superior mesenteric artery syndrome.
    Dig Surg. 2007;24(3):149-56
  • Kienle P, Büchler MW.
    Laparoscopic or open appendectomy for complicated appendicitis?
    Nat Clin Pract Gastroenterol Hepatol. 2006 Dec;3(12):668-9
  • Kienle P, Post S
    Chronisch entzündliche Darmerkrankungen
    Allgemeine und Viszeralchirurgie Update 2008, 1: 61-84
  • Weitz J, Weigand MA, Kienle P, Jager D, Buchler MW, Martin E.
    Importance of anesthesia in multimodal oncologic therapeutical concepts
    Anaesthesist 2006 Dec;55(12):1299-306
  • Kienle P, Weitz J, Koch M, Buchler MW.
    Laparoscopic surgery for colorectal cancer.
    Colorectal Dis 2006; 8 Suppl 3:33-36
  • Kienle P, Schaible A, Büchler MW
    Gastrointestinale Blutungen
    Intensivmedizin up2date 2006; 1: 73-85
  • Witte S, Knaebel HP, Kienle P, Seiler CM
    Project selection and protocol design in the Study Centre of the German Surgical Society
    Chirurg 2006; 77: 531-534
  • Knaebel HP, Kienle P
    Patients at risk of familial colorectal cancer.
    BMJ 2005 5; 331: 1033-1034
  • Kienle P, Leowardi C, Büchler MW, Schmidt J
    Colitis ulcerosa
    Coloproctology 2005; 27: 295-306
  • Knaebel HP, Kienle P, Buchler MW, Weitz J
    Surgical strategies for the prevention of gastrointestinal tumours
    Z Gastroenterol 2005; 43: 257-266
  • Koch M, Kienle P, Antolovic D, Buchler MW, Weitz J
    Is the lateral lymph node compartment relevant?
    Recent Results Cancer Res 2005;165: 40-45; medline gelistet, keine Impactpunkte
  • Leowardi C, Heuschen G, Kienle P, Heuschen U, Schmidt J.
    Surgical treatment of severe inflammatory bowel diseases.
    Dig Dis 2003; 21: 54-62
  • Kienle P, Koch M
    Are „micrometastases of the peritoneum equivalent to distant metastases?
    Dig Surg 2002; 19:453-458 Review
  • Schmidt J, Heuschen U, Eisold S, Kienle P, Klar E
    Notfälle beim Morbus Crohn: Wann soll operiert werden?
    Chir Gastroenterol 2002, 18: 230-237
  • Kienle P, Koch M
    Minimal residual disease in gastrointestinal cancer
    Semin Surg Oncol 2001, 20(4):282-93
  • Lehnert T, Kienle P, Maksan S, Herfarth C
    Standardresektion und Lymphadenektomie beim Magenkarzinom
    Chir Gastroenterol 1999; 15: 227-236
  • Stern J, Kienle P
    Vital preoperative function diagnosis in deep anterior rectum resection
    Chirurg 1996; 67(2):129-32

3. Fallberichte

  • Welsch T, Mechtersheimer G, Aulmann S, Mueller SA, Buechler MW, Schmidt J, Kienle P.
    Huge primitive neuroectodermal tumor of the pancreas: report of a case and review of the literature.
    World J Gastroenterol. 2006 Oct 7;12(37):6070-3
  • Weitz J, Kienle P, Bohrer H, Hofmann W, Theilmann L, Otto G
    Fatal hepatic necrosis after isoflurane anaesthesia
    Anaesthesia 1997; 52(9):892-5
  • Koch M, Kienle P, Fritz T, Meeder PJ
    The subacromial shoulder dislocation
    Chirurg 1999; 70(11):1361-3

4. Buchbeiträge

  • Kienle, Rogler.
    Fisteln (Kapitel 4.4)
    In:  Entzündliche Darmerkrankungen. Klinik, Diagnostik und Therapie
    2016 Schattauer GmbH
    Eds.: Eduard F. Stange
  • Kienle P
    Colitis ulcerosa (Kapitel 16.2)
    In:  Expertise Allgemein-und Viszeralchirurgie
    2016 Georg Thieme Verlag KG
    Eds.: Marco Sailer, Felix Aigner, Franc Hetzer
  • Peter Kienle und Stefan Post
    Chronisch-entzündliche Darmerkrankungen: Morbus Crohn und Colitis ulcerosa (Kapitel 12)
    In.: Allgemein- und Viszeralchirurgie II Spezielle operative Techniken
    2015 | 3. Auflage, Urban & Fischer in Elsevier (Verlag)
    Eds.: Heinz Becker, Michael Ghadimi
  • Kienle P., Hardt J
    Was gibt es Neues in der Chirurgie chronisch entzündlicher Darmerkrankungen?
    In: Was gibt es Neues in der Chirurgie?
    2013 ecomed Medizin
    Eds.: Jähne, Königsrainer, Südkamp, Schröder
  • Kienle P, Schaible A, Knaebel H.-P., Büchler M.W.
    Gastrointestinale Blutungen (Kapitel 21)
    In: Intensivmedizin,  2. Ed.
    2007 Georg Thieme Verlag KG
    Eds.: Van Aken, Reinhard, Welte, Zimpfer

5. Paper

  • [TaTME is an experimental procedure].
    Holmer C, Benz S, Fichtner-Feigl S, Jehle EC, Kienle P, Post S, Schiedeck T, Weitz J, Kreis ME.
    Chirurg. 2019 Jun;90(6):489-492. doi: 10.1007/s00104-019-0979-0. German. No abstract available.
  • Lateral pararectal versus transrectal stoma placement for prevention of parastomal herniation.
    Hardt J, Meerpohl JJ, Metzendorf MI, Kienle P, Post S, Herrle F.
    Cochrane Database Syst Rev. 2019 Apr 24;4:CD009487. doi: 10.1002/14651858.CD009487.pub3.
  • [Transanal total mesorectal excision-a critical appraisal].
    Holmer C, Benz S, Fichtner-Feigl S, Jehle EC, Kienle P, Post S, Schiedeck T, Weitz J, Kreis ME.
    Chirurg. 2019 Jun;90(6):478-486. doi: 10.1007/s00104-019-0945-x. Review. German.

Publikationen aus der Gastroenterologie


  • Schmitz D, Vogl T, Nour-Eldin NA, Radeleff B, Kröger JC, Mahnken AH, Ittrich H, Gehl HB, Plessow B, Böttcher J, Tacke J, Wispler M, Rosien U, Schorr W, Joerdens M, Glaser N, Fuchs ES, Tal A, Friesenhahn-Ochs B, Leimbach T, Höpner L, Weber M, Gölder S, Böhmig M, Hetjens S, Rudi J, Schegerer A. Patient radiation dose in percutaneous biliary interventions: recommendations for DRLs on the basis of a multicentre study. Eur Radiol. 2019 Jul;29(7):3390-3400
  • Schmitz D, Weller N, Doll M, Werle S, Mees C, Prinz P, John B, Schmidt D, Günther A, Weiß R,
    Rudi J. Is Insertion of a Plastic Stent better and safer than Epinephrine Injection in Post Sphincterotomy-Bleeding? European Journal of Gastroenterology & Hepatology (accepted July 2019)

Publikationen aus der Gynäkologie und Geburtshilfe

  • Arch Gynecol Obstet. 2019 Apr;299(4):1121-1130. doi: 10.1007/s00404-018-5025-9. Epub 2019 Jan 4.
    Patient preferences regarding intraoperative versus external beam radiotherapy for early breast cancer and the impact of socio-demographic factors.
    Spaich S1, Krickeberg S2, Hetjens S3, Wenz F4, Gerhardt A2,5, Sütterlin M2.
  • Front Oncol. 2018 Nov 21;8:535. doi: 10.3389/fonc.2018.00535. eCollection 2018.
    Patient Preferences Regarding Chemotherapy in Metastatic Breast Cancer-A Conjoint Analysis for Common Taxanes.
    Spaich S1, Kinder J1, Hetjens S2, Fuxius S3, Gerhardt A1,4, Sütterlin M1.

Publikationen aus der Urologie

  • Risks in healthcare: recognize, avoid, assess
    Köhrmann KU.
    Urologe A. 2018 Jul;57(7):783-784. doi: 10.1007/s00120-018-0694-3. German. No abstract available.
  • Focal therapy of prostate cancer
    Ganzer R, Franiel T, Köllermann J, Kuru T, Baumunk D, Blana A, Hadaschik B, von Hardenberg J, Henkel T, Köhrmann KU, Liehr UB, Machtens S, Roosen A, Salomon G, Schlemmer HP, Sentker L, Wendler J, Witzsch U, Schostak M.
    Urologe A. 2017 Oct;56(10):1335-1346. doi: 10.1007/s00120-017-0488-z. German.
  • MRI/TRUS fusion-guided prostate biopsy : Value in the context of focal therapy
    Franz T, von Hardenberg J, Blana A, Cash H, Baumunk D, Salomon G, Hadaschik B, Henkel T, Herrmann J, Kahmann F, Köhrmann KU, Köllermann J, Kruck S, Liehr UB, Machtens S, Peters I, Radtke JP, Roosen A, Schlemmer HP, Sentker L, Wendler JJ, Witzsch U, Stolzenburg JU, Schostak M, Ganzer R.
    Urologe A. 2017 Feb;56(2):208-216. doi: 10.1007/s00120-016-0268-1. Review. German.
  • Why we should not routinely apply irreversible electroporation as an alternative curative treatment modality for localized prostate cancer at this stage.
    Wendler JJ, Ganzer R, Hadaschik B, Blana A, Henkel T, Köhrmann KU, Machtens S, Roosen A, Salomon G, Sentker L, Witzsch U, Schlemmer HP, Baumunk D, Köllermann J, Schostak M, Liehr UB.
    World J Urol. 2017 Jan;35(1):11-20. doi: 10.1007/s00345-016-1838-y. Epub 2016 May 4. Review.
  • Focal therapy for small renal masses : Observation, ablation or surgery
    Wendler JJ, Friebe B, Baumunk D, Blana A, Franiel T, Ganzer R, Hadaschik B, Henkel T, Köhrmann KU, Köllermann J, Kuru T, Machtens S, Roosen A, Salomon G, Schlemmer HP, Sentker L, Witzsch U, Liehr UB, Ricke J, Schostak M.
    Urologe A. 2016 May;55(5):594-606. doi: 10.1007/s00120-016-0075-8. Review. German.

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